Methylcobalamin

Offer Details

Offer Type:
Offer Group:	food additive
Offer Post Time:	2009-11-08
Expiration Date:	2010-05-13
Details:	Methylcobalamin (JPIV) Methylcobalamin is a cobalamin (MeB12) used in peripheral neuropathy, diabetic neuropathy etc. It is a form of vitamin B12. This vitamer is one of two active coenzymes used by B-12 dependent enzymes in the body, and is specifically the B-12 form used by 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR), also known as methionine synthase. Methylcobalamin has been studied in conjunction with sleep-wake rhythm disorders, where it appears to yield benefits, but at a low or inconsistent level. [1] It is used in treating diseases of vitamin B12 deficiency (such as pernicious anemia), or diseases of effective B12 deficiency, such as vitamin B12 metabolic pathway pathologies. One study suggests that once absorbed, methylcobalamin may be retained in the body better than cyanocobalamin. [2] Technical specification: Characters: Dark-red crystalline powder or crystals Identification: UV: Compare the spectrum with the reference spectrum Chemical: Positive Solution purity: Clear and red color Related substances (HPLC) Total content (%) 2.0 max. Max. Related substance: 0.5max. Water (%): 12.0 max. Assay (on anhydrous basis) (%): 98.0 min. Residual solvents Ethanol (ppm): 5000max. Acetone (ppm): 5000max. Packing & Storage: 5000GM, 1000GM, 500GM, 200GM, 100GM, 50GM self-designed Aluminum bottle Storage: Light-resistant and dry, normal temperature.